Biology for Better Business

Today, we look to a future powered by nature where biological wonders produce new transformations including more and better food, renewable fuel for transportation, access to clean water, and longer, healthier lives. Ultimately, it will be you and millions of others that demand it.

Fighting Climate Change, One Laundry Load at a Time

Experts in the study of fungi are playing a bigger role in improving
laundry detergents and, by extension, leading efforts to cut energy use.

Ms. Sasa collecting a mushroom in the forest. Credit Carsten Snejbjerg for The New York Times

A Novozymes researcher, Leigh Murphy, performing tests on pieces of cloth. Credit Carsten Snejbjerg for The New York Times
Models of stain-fighting enzymes, displayed on clothes in a washing machine. Credit Carsten Snejbjerg for The New York Times

In 1833, French scientists isolated an enzyme for the first time. Known as diastase, it broke starch down into sugars. By the early 20th century, a German chemist had commercialized the technology, selling a detergent that included enzymes extracted from the guts of cows.

Novozymes and its rivals have developed a catalog of enzymes over the years, supplying them to consumer goods giants like Unilever and Procter & Gamble.

At the company’s low-slung 1960s-style campus, scientists in white lab coats and armed with miniature washing machines test new enzyme combinations on doll-size cutouts of clothing. To test a product’s stain-fighting prowess, they import stain samples from around the world, like greasy, blackened collars and yellow armpit stains.

Modern detergents contain as many as eight different enzymes. In 2016, Novozymes generated about $2.2 billion in revenue and provided enzymes for detergents including Tide, Ariel and Seventh Generation.

The quantity of enzymes required in a detergent is relatively small compared with chemical alternatives, an appealing quality for customers looking for more natural ingredients. A tenth of a teaspoon of enzymes in a typical European laundry load cuts by half the amount of soap from petrochemicals or palm oil in a detergent.

Enzymes are also well suited to helping cut energy consumption. They are often found in relatively cool environments, like forests and oceans. As a result of that low natural temperature, they do not require the heat and pressure typically used in washing machines and other laundry processes.

Novozymes and its rivals have developed a catalog of enzymes over the years, supplying them to consumer goods giants like Unilever and Procter & Gamble. Credit Carsten Snejbjerg for The New York Times
A wastewater treatment facility at the Novozymes factory in Kalundborg, Denmark. Credit Carsten Snejbjerg for The New York Times
Bags of granulated enzymes ready to be shipped from a Novozymes warehouse, where Claus Olsen was operating machinery. Credit Carsten Snejbjerg for The New York Times

So consumers can reduce the temperatures on their washing machines while ensuring their shirts stay lily white. Lowering the temperature on a washing machine cycle to cold water from 40 degrees Celsius (104 degrees Fahrenheit) reduces energy consumption by at least half, according to the International Association for Soaps, Detergents and Maintenance Products, an industry group.

“We think there are a lot of systems and processes in nature that are extremely resource efficient,” said Gerard Bos, director of the global business and biodiversity program at the International Union for Conservation of Nature in Switzerland. “In nature, there is basically no waste. Every material gets reused.”

In 2009, Novozymes scientists teamed up with Procter & Gamble to develop an enzyme that could be used in liquid detergents for cold-water washes. Researchers started with an enzyme from soil bacteria in Turkey, and modified it through genetic engineering to make it more closely resemble a substance found in cool seawater. When they found the right formula, they called the enzyme Everest, a reference to the scale of the task accomplished.

“We knew this was something that consumers would want,” said Phil Souter, associate director of Procter & Gamble’s research and development unit in Newcastle, England. “I think this is a very tangible and practical way people can make a difference in their everyday lives.”

Ms. Sasa and Ms. Landvik with their mushrooms in a lab. Credit Carsten Snejbjerg for The New York Times

Next, they found a way to mass produce the enzyme. Novozymes implanted the newly developed product’s DNA into a batch of microbial hosts used to cultivate large volumes of enzymes quickly and at low cost. The enzymes were then “brewed” in large, closely monitored tanks before being sold.

The result: a crucial ingredient in detergents like Tide Cold Water.

“This is biotechnology on a very large scale,” said Jes Bo Tobiassen, the manager of a Novozymes manufacturing facility in Kalundborg, a small coastal city in Denmark.

As it researches new enzymes, Novozymes is trying to reach consumers in fast-growing economies, like China.

In much of the developed world, laundry habits are relatively entrenched. Europeans tend to use front-loading washers, which are far more efficient in energy and water use than the top-loaders favored in the United States.

Peder Holk Nielsen, the chief executive of Novozymes, said the development of enzymes for washing clothes could be “a phenomenal sustainability story.” Credit Carsten Snejbjerg for The New York Times

But in China, members of the growing middle class like Shen Hang are upgrading washing machines and turning to more expensive, higher-quality detergents. While Chinese consumers are among the world’s most frequent and fastidious washers of clothes, according to Novozymes researchers, they aren’t as set in their ways.

Mr. Shen recently bought an efficient front-loading washer-dryer. But he has struggled to find a detergent that can get his sweat-stained shirt collars clean.

“I’m kind of sick of that,” he said of manufacturers’ exaggerated claims.

He uses two types of bleach, one for white clothes and one for colored. If they do not work, he manually rubs the stains with his hands. He repeats that cycle three times a week.

Sensing an opportunity, Novozymes’s commercial teams have pushed the company’s scientists to create enzymes that would perform better in the bleach-filled washes favored in China.

The company has made progress. A newly developed enzyme named Progress Uno is being added to liquid detergents manufactured by Liby, a Chinese company.

At this point, Chinese consumers mostly wash at low temperatures. But Peder Holk Nielsen, the chief executive of Novozymes, worries that could change as wealth in China grows. Consumers did the same in the West in the decades after World War II, Mr. Nielsen said.

But if, thanks to enzyme development, that transition can be avoided, that would be “a phenomenal sustainability story,” he said. “It is going to save so much water, and so much energy.”

Fungus isolated from soil and grown for research at Novozymes. Credit Carsten Snejbjerg for The New York Times
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